Structural Alert/Reactive Metabolite Concept as Applied in Medicinal Chemistry to Mitigate the Risk of Idiosyncratic Drug Toxicity: A Perspective Based on the Critical Examination of Trends in the Top 200 Drugs Marketed
Discovery and quality analysis of a comprehensive set of structural variants and short tandem repeats | Nature Communications
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TFEB induces mitochondrial itaconate synthesis to suppress bacterial growth in macrophages | Nature Metabolism
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Inherited PD-1 deficiency underlies tuberculosis and autoimmunity in a child | Nature Medicine
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Discovery of Novel N-Hydroxy-1,2,4-oxadiazole-5-formamides as ASM Direct Inhibitors for the Treatment of Atherosclerosis | Journal of Medicinal Chemistry
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SREBP1-induced fatty acid synthesis depletes macrophages antioxidant defences to promote their alternative activation | Nature Metabolism
