![Cancers | Free Full-Text | p53-Mediated Tumor Suppression: DNA-Damage Response and Alternative Mechanisms Cancers | Free Full-Text | p53-Mediated Tumor Suppression: DNA-Damage Response and Alternative Mechanisms](https://pub.mdpi-res.com/cancers/cancers-11-01983/article_deploy/html/images/cancers-11-01983-g001.png?1577715103)
Cancers | Free Full-Text | p53-Mediated Tumor Suppression: DNA-Damage Response and Alternative Mechanisms
![How does p53 induce apoptosis and how does this relate to p53-mediated tumour suppression? | Cell Death & Differentiation How does p53 induce apoptosis and how does this relate to p53-mediated tumour suppression? | Cell Death & Differentiation](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fcdd.2017.169/MediaObjects/41418_2018_Article_BFcdd2017169_Fig1_HTML.jpg)
How does p53 induce apoptosis and how does this relate to p53-mediated tumour suppression? | Cell Death & Differentiation
![Endoplasmic Reticulum Stress-induced Apoptosis: MULTIPLE PATHWAYS AND ACTIVATION OF p53-UP-REGULATED MODULATOR OF APOPTOSIS (PUMA) AND NOXA BY p53 - ScienceDirect Endoplasmic Reticulum Stress-induced Apoptosis: MULTIPLE PATHWAYS AND ACTIVATION OF p53-UP-REGULATED MODULATOR OF APOPTOSIS (PUMA) AND NOXA BY p53 - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S0021925819353475-gr9.jpg)
Endoplasmic Reticulum Stress-induced Apoptosis: MULTIPLE PATHWAYS AND ACTIVATION OF p53-UP-REGULATED MODULATOR OF APOPTOSIS (PUMA) AND NOXA BY p53 - ScienceDirect
![Both p53–PUMA/NOXA–Bax-mitochondrion and p53–p21cip1 pathways are involved in the CDglyTK-mediated tumor cell suppression - ScienceDirect Both p53–PUMA/NOXA–Bax-mitochondrion and p53–p21cip1 pathways are involved in the CDglyTK-mediated tumor cell suppression - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S0006291X09012212-gr4.jpg)
Both p53–PUMA/NOXA–Bax-mitochondrion and p53–p21cip1 pathways are involved in the CDglyTK-mediated tumor cell suppression - ScienceDirect
BH3-only sensors Bad, Noxa and Puma are Key Regulators of Tacaribe virus-induced Apoptosis | PLOS Pathogens
![Puma, noxa, p53, and p63 differentially mediate stress pathway induced apoptosis | Cell Death & Disease Puma, noxa, p53, and p63 differentially mediate stress pathway induced apoptosis | Cell Death & Disease](https://media.springernature.com/lw685/springer-static/image/art%3A10.1038%2Fs41419-021-03902-6/MediaObjects/41419_2021_3902_Fig1_HTML.png)
Puma, noxa, p53, and p63 differentially mediate stress pathway induced apoptosis | Cell Death & Disease
![NOXA upregulation by the prohibitin‐binding compound fluorizoline is transcriptionally regulated by integrated stress response‐induced ATF3 and ATF4 - Núñez‐Vázquez - 2021 - The FEBS Journal - Wiley Online Library NOXA upregulation by the prohibitin‐binding compound fluorizoline is transcriptionally regulated by integrated stress response‐induced ATF3 and ATF4 - Núñez‐Vázquez - 2021 - The FEBS Journal - Wiley Online Library](https://febs.onlinelibrary.wiley.com/cms/asset/212d97fc-749c-4b4b-9b2f-f2d8ca4812c8/febs15480-fig-0008-m.jpg)
NOXA upregulation by the prohibitin‐binding compound fluorizoline is transcriptionally regulated by integrated stress response‐induced ATF3 and ATF4 - Núñez‐Vázquez - 2021 - The FEBS Journal - Wiley Online Library
![A review of the role of Puma, Noxa and Bim in the tumorigenesis, therapy and drug resistance of chronic lymphocytic leukemia | Cancer Gene Therapy A review of the role of Puma, Noxa and Bim in the tumorigenesis, therapy and drug resistance of chronic lymphocytic leukemia | Cancer Gene Therapy](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fcgt.2012.84/MediaObjects/41417_2013_Article_BFcgt201284_Fig1_HTML.jpg)
A review of the role of Puma, Noxa and Bim in the tumorigenesis, therapy and drug resistance of chronic lymphocytic leukemia | Cancer Gene Therapy
![Mechanisms of Noxa-induced apoptosis. Noxa can induce apoptosis via... | Download Scientific Diagram Mechanisms of Noxa-induced apoptosis. Noxa can induce apoptosis via... | Download Scientific Diagram](https://www.researchgate.net/publication/323658443/figure/fig1/AS:711372014899203@1546615713229/Fig-1-Mechanisms-of-Noxa-induced-apoptosis-Noxa-can-induce-apoptosis-via.png)
Mechanisms of Noxa-induced apoptosis. Noxa can induce apoptosis via... | Download Scientific Diagram
![Role of PUMA NOXA and BAX in the oocyte DNA-damage checkpoint Asterisks... | Download Scientific Diagram Role of PUMA NOXA and BAX in the oocyte DNA-damage checkpoint Asterisks... | Download Scientific Diagram](https://www.researchgate.net/publication/341621195/figure/fig5/AS:959167447695393@1605694748985/Role-of-PUMA-NOXA-and-BAX-in-the-oocyte-DNA-damage-checkpoint-Asterisks-represent.png)
Role of PUMA NOXA and BAX in the oocyte DNA-damage checkpoint Asterisks... | Download Scientific Diagram
![Both p53-PUMA/NOXA-Bax-mitochondrion and p53-p21cip1 pathways are involved in the CDglyTK-mediated tumor cell suppression. | Semantic Scholar Both p53-PUMA/NOXA-Bax-mitochondrion and p53-p21cip1 pathways are involved in the CDglyTK-mediated tumor cell suppression. | Semantic Scholar](https://d3i71xaburhd42.cloudfront.net/cc90d7cdcb819e4cb188aa41d202946fb22d868f/4-Figure4-1.png)
Both p53-PUMA/NOXA-Bax-mitochondrion and p53-p21cip1 pathways are involved in the CDglyTK-mediated tumor cell suppression. | Semantic Scholar
![The role of P53 up-regulated modulator of apoptosis (PUMA) in ovarian development, cardiovascular and neurodegenerative diseases | SpringerLink The role of P53 up-regulated modulator of apoptosis (PUMA) in ovarian development, cardiovascular and neurodegenerative diseases | SpringerLink](https://media.springernature.com/lw685/springer-static/image/art%3A10.1007%2Fs10495-021-01667-z/MediaObjects/10495_2021_1667_Fig3_HTML.png)